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Therapeutic efficacy of a polymyxin B-dextran 70 conjugate in experimental model of endotoxemia.

Numerous studies have suggested that lipopolysaccharide (LPS), a major component of the cell wall of gram-negative bacteria, is responsible for the initiation of gram-negative septic shock. Previously, others have designed therapeutic regimens to target the biologically active lipid A region of LPS...

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Библиографические подробности
Опубликовано в::Antimicrob Agents Chemother
Главные авторы: Bucklin, S E, Lake, P, Lögdberg, L, Morrison, D C
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1995
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1462
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