Intracellular accumulation of ofloxacin-loaded liposomes in human synovial fibroblasts.

In order to incorporate ofloxacin within liposomes, the reverse-phase evaporation technique was carried out. The liposome lipid matrix consisted of dipalmitoylphosphatidylcholine-cholesterol-dihexadecylphosphate (4: 3:4 molar ratio). The liposome formulation presented a mean size of 185 +/- 31 nm an...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Fresta, M, Spadaro, A, Cerniglia, G, Ropero, I M, Puglisi, G, Furneri, P M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574534/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.6.1372
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