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The PETT series, a new class of potent nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase.

To identify the minimal structural elements necessary for biological activity, the rigid tricyclic nucleus of the known human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) inhibitor tetrahydroimidazobenzodiazepinthione was subjected to systematic bond disconnection to obtain simpl...

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Published in:Antimicrob Agents Chemother
Main Authors: Ahgren, C, Backro, K, Bell, F W, Cantrell, A S, Clemens, M, Colacino, J M, Deeter, J B, Engelhardt, J A, Hogberg, M, Jaskunas, S R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.6.1329
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