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Intracellular Evaluation of ER Targeting Elucidates a Mild Form of Inherited Coagulation Deficiency
Missense mutations reduce protein levels through several molecular mechanisms. Among them, altered targeting to endoplasmic reticulum (ER) and its relationship with clinical phenotypes in patients have been poorly investigated. To address this point, we studied the prepeptide mutations (L-48P, L-42P...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
ScholarOne
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1626593/ https://ncbi.nlm.nih.gov/pubmed/17088945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2005-00040.Rizzotto |
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