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Target for bacteriostatic and bactericidal activities of beta-lactam antibiotics against Escherichia coli resides in different penicillin-binding proteins.

The relationship between cell-killing kinetics and penicillin-binding protein (PBP) saturation has been evaluated in the permeability mutant Escherichia coli DC2 in which the antimicrobial activity of beta-lactams has been described as being directly related to the extent of saturation of the PBP ta...

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Bibliographische Detailangaben
Hauptverfasser: Satta, G, Cornaglia, G, Mazzariol, A, Golini, G, Valisena, S, Fontana, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162634/
https://ncbi.nlm.nih.gov/pubmed/7785976
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