In vitro effects of sulfadiazine and its metabolites alone and in combination with pyrimethamine on Toxoplasma gondii.

Sulfadiazine and the metabolites N4-acetyl-sulfadiazine, 4-OH-sulfadiazine, 5-OH-sulfadiazine, 5-OH-glucuronide-sulfadiazine, and 5-OH-sulfate-sulfadiazine were tested separately and in combination with pyrimethamine for the inhibitory activity on Toxoplasma gondii growth in vitro. Except for N4-ace...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Schoondermark-van de Ven, E, Vree, T, Melchers, W, Camps, W, Galama, J
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7793889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.39.3.763
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