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Use of normal C57BL/6 mice with established Mycobacterium avium infections as an alternative model for evaluation of antibiotic activity.

Several murine models have been used to evaluate the activities of antimicrobial agents against Mycobacterium avium infection. The main model used is the beige mouse model, but beige mice are expensive and not easily available. Thus, we developed a model of infection in wild C57BL/6 mice. The drugs...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Cohen, Y, Perronne, C, Lazard, T, Truffot-Pernot, C, Grosset, J, Vilde, J L, Pocidalo, J J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162614/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7793882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.39.3.735
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