Mechanism of enhanced antipseudomonal activity of BO-2727, a new injectable 1-beta-methyl carbapenem.

The mechanism of the enhanced activity of BO-2727 against imipenem-resistant Pseudomonas aeruginosa was studied by using a set of four isogenic strains derived from beta-lactamase-deficient P. aeruginosa PAO4089 (blaJ blaP). Complementation of the blaJ and blaP mutations conferred greater resistance...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Hazumi, N, Fuse, A, Matsuda, K, Hashizume, T, Sanada, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162608/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7793876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.39.3.702
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