Quinolone antibiotics in therapy of experimental pneumococcal meningitis in rabbits.

Using a rabbit model of pneumococcal meningitis, we compared the pharmacokinetics and bactericidal activities in cerebrospinal fluid (CSF) of older (ciprofloxacin, ofloxacin) and newer (levofloxacin, temafloxacin, CP-116,517, and Win 57273) quinolones with those of the beta-lactam ceftriaxone. All q...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Nau, R, Schmidt, T, Kaye, K, Froula, J L, Täuber, M G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162589/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7793857/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.39.3.593
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