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Molecular characterization of nine different types of mutants among 107 inhibitor-resistant TEM beta-lactamases from clinical isolates of Escherichia coli.

DNA-DNA hybridization and sequencing were performed to determine the molecular basis of resistance to clavulanic acid in 107 inhibitor-resistant TEM (IRT) enzymes produced by Escherichia coli clinical isolates. These beta-lactamases derived from TEM-1 enzyme focused at pI 5.2 (n = 68) or 5.4 (n = 39...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Henquell, C, Chanal, C, Sirot, D, Labia, R, Sirot, J
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162554/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7726509/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.2.427
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