Molecular characterization of nine different types of mutants among 107 inhibitor-resistant TEM beta-lactamases from clinical isolates of Escherichia coli.

DNA-DNA hybridization and sequencing were performed to determine the molecular basis of resistance to clavulanic acid in 107 inhibitor-resistant TEM (IRT) enzymes produced by Escherichia coli clinical isolates. These beta-lactamases derived from TEM-1 enzyme focused at pI 5.2 (n = 68) or 5.4 (n = 39...

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Main Authors: Henquell, C, Chanal, C, Sirot, D, Labia, R, Sirot, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162554/
https://ncbi.nlm.nih.gov/pubmed/7726509
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