Structure-activity relationships of carbapenems that determine their dependence on porin protein D2 for activity against Pseudomonas aeruginosa.

A number of carbapenem derivatives were examined to determine the structure-activity relationships required for dependence on porin protein D2 for activity against Pseudomonas aeruginosa. As suggested by J. Trias and H. Nikaido (Antimicrob. Agents Chemother. 34:52-57, 1990), carbapenem derivatives,...

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Autores principales: Fung-Tomc, J C, Huczko, E, Banville, J, Ménard, M, Kolek, B, Gradelski, E, Kessler, R E, Bonner, D P
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC162549/
https://ncbi.nlm.nih.gov/pubmed/7726504
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