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Chloroquine encapsulated in malaria-infected erythrocyte-specific antibody-bearing liposomes effectively controls chloroquine-resistant Plasmodium berghei infections in mice.

The suitability of liposomes as drug carriers in the treatment of drug-resistant rodent malaria was examined after covalently attaching F(ab')2 fragments of a mouse monoclonal antibody (MAb), MAb F10, raised against the host cell membranes isolated from the Plasmodium berghei-infected mouse erythroc...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Owais, M, Varshney, G C, Choudhury, A, Chandra, S, Gupta, C M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1995
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162506/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695303/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.1.180
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