Immediate zidovudine treatment protects simian immunodeficiency virus-infected newborn macaques against rapid onset of AIDS.

Simian immunodeficiency virus (SIV) infection of newborn rhesus macaques is a practical animal model of pediatric AIDS. Intravenous inoculation of rhesus newborns with uncloned SIVmac resulted in a high virus load, no antiviral immune responses, severe immunodeficiency, and a high mortality rate wit...

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Bibliographic Details
Main Authors: Van Rompay, K K, Otsyula, M G, Marthas, M L, Miller, C J, McChesney, M B, Pedersen, N C
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC162497/
https://ncbi.nlm.nih.gov/pubmed/7695293
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