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Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.

Twenty-eight 2,4-diaminopteridines with alkyl and aralkyl groups at the 6- and 7-positions, five 1,3-diamino-7,8,9,10-tetrahydropyrimido [4,5-c]isoquinolines with an alkyl, alkylthio, or aryl group at the 6-position, and nine 4,6-diamino-1,2-dihydro-s-triazines with one or two alkyl groups at the 2-...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Rosowsky, A, Hynes, J B, Queener, S F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162489/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695334/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.1.79
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