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Long-chain alkanoylcholines, a new category of soft antimicrobial agents that are enzymatically degradable.

A new category of amphiphilic hydrolyzable quaternary ammonium compounds with rapid and high levels of antimicrobial activity was studied. The compounds, alkanoylcholines with hydrocarbon chains of 10 to 14 carbon atoms, are hydrolyzed by butyrylcholine esterase, which is present in human serum and...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Ahlström, B, Chelminska-Bertilsson, M, Thompson, R A, Edebo, L
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162483/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7695328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.1.50
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