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Specific interaction of heterogeneous nuclear ribonucleoprotein A1 with the –219T allelic form modulates APOE promoter activity
The polymorphic –219T/G variant in the APOE promoter has been associated with variations in basal transcriptional activity as well as with the risk of developing Alzheimer’s disease, myocardial infarction and early-onset coronary heart disease. The molecular mechanisms underlying these effects are p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC162339/ https://ncbi.nlm.nih.gov/pubmed/12799433 |
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