The C-terminal domain of Escherichia coli MutY is involved in DNA binding and glycosylase activities
Escherichia coli MutY is an adenine and a weak guanine DNA glycosylase involved in reducing mutagenic effects of 7,8-dihydro-8-oxo-guanine (8-oxoG). The C-terminal domain of MutY is required for 8-oxoG recognition and is critical for mutation avoidance of oxidative damage. To determine which residue...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162338/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12799430/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg434 |
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