Luminal NaCl delivery regulates basolateral PGE(2) release from macula densa cells

Macula densa (MD) cells express COX-2 and COX-2–derived PGs appear to signal the release of renin from the renal juxtaglomerular apparatus, especially during volume depletion. However, the synthetic machinery and identity of the specific prostanoid released from intact MD cells remains uncertain. In...

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Autores principales: Peti-Peterdi, János, Komlosi, Peter, Fuson, Amanda L., Guan, Youfei, Schneider, André, Qi, Zhonghua, Redha, Reyadh, Rosivall, Laszlo, Breyer, Matthew D., Bell, P. Darwin
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC162292/
https://ncbi.nlm.nih.gov/pubmed/12840061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318018
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