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G protein-coupled receptors sense fluid shear stress in endothelial cells

Hemodynamic shear stress stimulates a number of intracellular events that both regulate vessel structure and influence development of vascular pathologies. The precise molecular mechanisms by which endothelial cells transduce this mechanical stimulus into intracellular biochemical response have not...

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Bibliographic Details
Main Authors: Chachisvilis, Mirianas, Zhang, Yan-Liang, Frangos, John A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622845/
https://ncbi.nlm.nih.gov/pubmed/17030791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607224103
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