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Characterization of a Novel Origin Recognition Complex-Like Complex: Implications for DNA Recognition, Cell Cycle Control, and Locus-Specific Gene Amplification

The origin recognition complex (ORC) plays a central role in eukaryotic DNA replication. Here we describe a unique ORC-like complex in Tetrahymena thermophila, TIF4, which bound in an ATP-dependent manner to sequences required for cell cycle-controlled replication and gene amplification (ribosomal D...

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Detalhes bibliográficos
Main Authors: Mohammad, Mohammad, York, Randall D., Hommel, Jonathan, Kapler, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162205/
https://ncbi.nlm.nih.gov/pubmed/12832485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.14.5005-5017.2003
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