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Production of leukotrienes in a model of focal cerebral ischaemia in the rat

1. The aim of this work was to evaluate the role of leukotrienes in brain damage in vivo in a model of focal cerebral ischaemia in the rat, obtained by permanent occlusion of middle cerebral artery. 2. A significant (P<0.01) elevation of LTC(4), LTD(4) and LTE(4) (cysteinyl-leukotrienes) levels o...

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Detalhes bibliográficos
Main Authors: Ciceri, Paola, Rabuffetti, Monica, Monopoli, Angela, Nicosia, Simonetta
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1621141/
https://ncbi.nlm.nih.gov/pubmed/11498518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704189
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