Salmonella enterica Serovar Typhimurium Expressing a Chromosomally Integrated Copy of the Bacillus anthracis Protective Antigen Gene Protects Mice against an Anthrax Spore Challenge

Protective immunity against infection with Bacillus anthracis is almost entirely based on a response to the protective antigen (PA), the binding moiety for the two other toxin components. We cloned the PA gene into an auxotrophic mutant of Salmonella enterica serovar Typhimurium as a fusion with the...

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Autori principali: Garmory, Helen S., Titball, Richard W., Griffin, Kate F., Hahn, Ulrike, Böhm, Reinhard, Beyer, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Microbial Immunity and Vaccines
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC162028/
https://ncbi.nlm.nih.gov/pubmed/12819066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.3831-3836.2003
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