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Functional overlap of sequences that activate transcription and signal ubiquitin-mediated proteolysis

Many transcription factors, particularly those involved in the control of cell growth, are unstable proteins destroyed by ubiquitin-mediated proteolysis. In a previous study of sequences targeting the transcription factor Myc for destruction, we observed that the region in Myc signaling ubiquitin-me...

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Hlavní autoři: Salghetti, Simone E., Muratani, Masafumi, Wijnen, Herman, Futcher, Bruce, Tansey, William P.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC16202/
https://ncbi.nlm.nih.gov/pubmed/10706616
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