Transforming Growth Factor α Binds to Trypanosoma cruzi Amastigotes To Induce Signaling and Cellular Proliferation

Macrophages secrete transforming growth factor α (TGF-α) to trigger proliferation of cancer cells. Here, we report a new role for TGF-α in modulating the direct cellular proliferation of a parasitic protozoan, Trypanosoma cruzi. Amastigotes present two classes of receptors for TGF-α with different b...

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Hlavní autoři: Alexander, A. Deloris, Villalta, Fernando, Lima, Maria F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2003
Témata:
Fungal and Parasitic Infections
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC162019/
https://ncbi.nlm.nih.gov/pubmed/12819119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.7.4201-4205.2003
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