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The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster

Most organisms have evolved defense mechanisms to protect themselves from viruses and other pathogens. Arthropods lack the protein-based adaptive immune response found in vertebrates. Here we show that the central catalytic component of the RNA-induced silencing complex (RISC), the nuclease Argonaut...

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Détails bibliographiques
Auteurs principaux: van Rij, Ronald P., Saleh, Maria-Carla, Berry, Bassam, Foo, Catherine, Houk, Andrew, Antoniewski, Christophe, Andino, Raul
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1620017/
https://ncbi.nlm.nih.gov/pubmed/17079687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1482006
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