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Differential Hyperacetylation of Histones H3 and H4 upon Promoter-Specific Recruitment of EBNA2 in Epstein-Barr Virus Chromatin

Epstein-Barr virus nuclear antigen 2 (EBNA2) is a transcriptional activator involved in the immortalization of B lymphocytes by the virus. EBNA2 is targeted to the promoters of its responsive genes, via interaction with cellular DNA-binding proteins. Using chromatin immunoprecipitation assays, we sh...

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Autors principals: Alazard, Nathalie, Gruffat, Henri, Hiriart, Edwige, Sergeant, Alain, Manet, Evelyne
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC161941/
https://ncbi.nlm.nih.gov/pubmed/12829856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.8166-8172.2003
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