The Viral σ1 Protein and Glycoconjugates Containing α2-3-Linked Sialic Acid Are Involved in Type 1 Reovirus Adherence to M Cell Apical Surfaces

Type 1 reoviruses invade the intestinal mucosa of mice by adhering selectively to M cells in the follicle-associated epithelium and then exploiting M cell transport activity. The purpose of this study was to identify the apical cell membrane component and viral protein that mediate the M cell adhere...

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Main Authors: Helander, Anna, Silvey, Katherine J., Mantis, Nicholas J., Hutchings, Amy B., Chandran, Kartik, Lucas, William T., Nibert, Max L., Neutra, Marian R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC161912/
https://ncbi.nlm.nih.gov/pubmed/12829836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.14.7964-7977.2003
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