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Mutation of MEF2A in an Inherited Disorder with Features of Coronary Artery Disease

The early genetic pathway(s) triggering the pathogenesis of coronary artery disease (CAD) and myocardial infarction (MI) remain largely unknown. Here, we describe an autosomal dominant form of CAD/MI (adCAD1) that is caused by the deletion of seven amino acids in transcription factor MEF2A. The dele...

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Autori principali: Wang, Lejin, Fan, Chun, Topol, Sarah E., Topol, Eric J., Wang, Qing
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618876/
https://ncbi.nlm.nih.gov/pubmed/14645853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1088477
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