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Ligand Valency Affects Transcytosis, Recycling and Intracellular Trafficking Mediated by the Neonatal Fc Receptor

The neonatal Fc receptor (FcRn) transports IgG across epithelial cell barriers to provide maternal antibodies to offspring and serves as a protection receptor by rescuing endocytosed IgG and albumin from lysosomal degradation. Here we describe the generation of polarized Madin–Darby canine kidney (M...

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Détails bibliographiques
Auteurs principaux: Tesar, Devin B, Tiangco, Noreen E, Bjorkman, Pamela J
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618808/
https://ncbi.nlm.nih.gov/pubmed/17004319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2006.00457.x
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