Ligand Valency Affects Transcytosis, Recycling and Intracellular Trafficking Mediated by the Neonatal Fc Receptor

The neonatal Fc receptor (FcRn) transports IgG across epithelial cell barriers to provide maternal antibodies to offspring and serves as a protection receptor by rescuing endocytosed IgG and albumin from lysosomal degradation. Here we describe the generation of polarized Madin–Darby canine kidney (M...

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Hlavní autoři: Tesar, Devin B, Tiangco, Noreen E, Bjorkman, Pamela J
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2006
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618808/
https://ncbi.nlm.nih.gov/pubmed/17004319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2006.00457.x
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