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Evaluation of Nucleoside Phosphonates and Their Analogs and Prodrugs for Inhibition of Orthopoxvirus Replication

In the event of a bioterrorism attack using smallpox virus, there currently is no approved drug for the treatment of infections with this virus. We have reported previously that (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (HPMPC) (also known as cidofovir [CDV]) has good activity against pox...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Keith, Kathy A., Hitchcock, Michael J. M., Lee, William A., Holý, Antonin, Kern, Earl R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161877/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12821467/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.7.2193-2198.2003
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