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Distinct Roles for Lymphotoxin-α and Tumor Necrosis Factor in the Control of Leishmania donovani Infection

Tumor necrosis factor (TNF) is critical for the control of visceral leishmaniasis caused by Leishmania donovani. However, the role of the related cytokine lymphotoxin (LT) α in this infection is unknown. Here we report that C57BL/6 mice deficient in TNF (B6.TNF(−/−)) or LTα (B6.LTα(−/−)) have increa...

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Detalhes bibliográficos
Main Authors: Engwerda, Christian R., Ato, Manabu, Stäger, Simona, Alexander, Clare E., Stanley, Amanda C., Kaye, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618729/
https://ncbi.nlm.nih.gov/pubmed/15579454
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