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Dysmorphogenesis of Kidney Cortical Peritubular Capillaries in Angiopoietin-2-Deficient Mice

Angiopoietin-2 (Ang-2) modulates Tie-2 receptor activation. In mouse kidney maturation, Ang-2 is expressed in arteries, with lower levels in tubules, whereas Tie-2 is expressed by endothelia. We hypothesized that Ang-2 deficiency disrupts kidney vessel patterning. The normal renal cortical peritubul...

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Bibliographische Detailangaben
Hauptverfasser: Pitera, Jolanta E., Woolf, Adrian S., Gale, Nicholas W., Yancopoulos, George D., Tao Yuan, Hai
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2004
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618709/
https://ncbi.nlm.nih.gov/pubmed/15579434
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