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Overexpression of Human Matrix Metalloproteinase-12 Enhances the Development of Inflammatory Arthritis in Transgenic Rabbits

Increased proteolytic activity of matrix metalloproteinases (MMPs) may promote articular destruction such as occurs in rheumatoid arthritis and osteoarthritis. Recently, we reported that synovial tissue and fluid obtained from patients with rheumatoid arthritis contained higher activity of macrophag...

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Détails bibliographiques
Auteurs principaux: Wang, Xiaofei, Liang, Jingyan, Koike, Tomonari, Sun, Huijun, Ichikawa, Tomonaga, Kitajima, Shuji, Morimoto, Masatoshi, Shikama, Hisataka, Watanabe, Teruo, Sasaguri, Yasuyuki, Fan, Jianglin
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618618/
https://ncbi.nlm.nih.gov/pubmed/15466401
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