Nephrin Forms a Complex with Adherens Junction Proteins and CASK in Podocytes and in Madin-Darby Canine Kidney Cells Expressing Nephrin

Mutations in the NPHS1 gene encoding nephrin lead to congenital nephrotic syndrome of the Finnish type. Nephrin is a key component of the glomerular slit diaphragms between epithelial foot processes, but its role in the pathogenesis of this disease is poorly understood. To further clarify the molecu...

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Autors principals: Lehtonen, Sanna, Lehtonen, Eero, Kudlicka, Krystyna, Holthöfer, Harry, Farquhar, Marilyn G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2004
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618613/
https://ncbi.nlm.nih.gov/pubmed/15331416
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