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Vitamin D(3) Induces Caspase-14 Expression in Psoriatic Lesions and Enhances Caspase-14 Processing in Organotypic Skin Cultures

Caspase-14 is a nonapoptotic caspase family member whose expression in the epidermis is confined to the suprabasal layers, which consist of differentiating keratinocytes. Proteolytic activation of this caspase is observed in the later stages of epidermal differentiation. In psoriatic skin, a dramati...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lippens, Saskia, Kockx, Mark, Denecker, Geertrui, Knaapen, Michiel, Verheyen, An, Christiaen, Ruben, Tschachler, Erwin, Vandenabeele, Peter, Declercq, Wim
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2004
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618612/
https://ncbi.nlm.nih.gov/pubmed/15331408
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