High-Level Expression of AmpC β-Lactamase Due to Insertion of Nucleotides between −10 and −35 Promoter Sequences in Escherichia coli Clinical Isolates: Cases Not Responsive to Extended-Spectrum-Cephalosporin Treatment

Two Escherichia coli isolates were recovered from the blood of two cancer patients and were demonstrated to produce high levels of the AmpC β-lactamase with isoelectric points of >9.0. The hypertranscription of ampC RNA was observed by Northern blot hybridization in both isolates. One isolate (is...

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Bibliographic Details
Main Authors: Siu, L. K., Lu, Po-Liang, Chen, J.-Y., Lin, F. M., Chang, Shan-Chwen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC161857/
https://ncbi.nlm.nih.gov/pubmed/12821459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.7.2138-2144.2003
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