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Molecular Analysis of the Human Autoantibody Response to α-Fodrin in Sjögren’s Syndrome Reveals Novel Apoptosis-Induced Specificity

Lymphocyte infiltration of salivary and lacrimal glands leading to diminished secretion and gland destruction as a result of apoptosis is thought to be pivotal in the pathogenesis of Sjögren’s syndrome (SS). The cytoskeletal protein α-fodrin is cleaved during this apoptotic process, and a strong ant...

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Hlavní autoři: Maruyama, Toshiaki, Saito, Ichiro, Hayashi, Yoshio, Kompfner, Elizabeth, Fox, Robert I., Burton, Dennis R., Ditzel, Henrik J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618543/
https://ncbi.nlm.nih.gov/pubmed/15215161
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