Inhibitory Effect of NO-Releasing Ciprofloxacin (NCX 976) on Mycobacterium tuberculosis Survival

Here, we report the antimycobacterial activity of NCX 976, a new molecule obtained adding a NO moiety to the fluoroquinolone ciprofloxacin, on Mycobacterium tuberculosis H37Rv strain, both in a cell-free model and in infected human macrophages. Unlike unaltered ciprofloxacin, NCX976 displayed a mark...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ciccone, R., Mariani, F., Cavone, A., Persichini, T., Venturini, G., Ongini, E., Colizzi, V., Colasanti, M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Action: Physiological Effects
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161842/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12821482/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.7.2299-2302.2003
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