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Proinsulin is encoded by an RNA splice variant in human blood myeloid cells
Genes for peripheral tissue-restricted self-antigens are expressed in thymic and hematopoietic cells. In thymic medullary epithelial cells, self-antigen expression imposes selection on developing autoreactive T cells and regulates susceptibility to autoimmune disease in mouse models. Less is known a...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1618309/ https://ncbi.nlm.nih.gov/pubmed/17053071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607380103 |
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