Repression of HMGA2 Gene Expression by Human Cytomegalovirus Involves the IE2 86-Kilodalton Protein and Is Necessary for Efficient Viral Replication and Inhibition of Cyclin A Transcription

Human cytomegalovirus (HCMV) infection results in dysregulation of several cell cycle genes, including inhibition of cyclin A transcription. In this work, we examine the effect of the HCMV infection on expression of the high-mobility group A2 (HMGA2) gene, which encodes an architectural transcriptio...

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Bibliographic Details
Main Authors: Shlapobersky, Mark, Sanders, Rebecca, Clark, Charles, Spector, Deborah H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617307/
https://ncbi.nlm.nih.gov/pubmed/17005673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01300-06
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