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Asynchronous Progression through the Lytic Cascade and Variations in Intracellular Viral Loads Revealed by High-Throughput Single-Cell Analysis of Kaposi's Sarcoma-Associated Herpesvirus Infection

Kaposi's sarcoma-associated herpesvirus (KSHV or human herpesvirus-8) is frequently tumorigenic in immunocompromised patients. The average intracellular viral copy number within infected cells, however, varies markedly by tumor type. Since the KSHV-encoded latency-associated nuclear antigen (LA...

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Библиографические подробности
Главные авторы: Adang, Laura A., Parsons, Christopher H., Kedes, Dean H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617294/
https://ncbi.nlm.nih.gov/pubmed/17005685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01156-06
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