Differential Enhancement of Dengue Virus Immune Complex Infectivity Mediated by Signaling-Competent and Signaling-Incompetent Human FcγRIA (CD64) or FcγRIIA (CD32)

Fcγ receptor (FcγR)-mediated entry of infectious dengue virus immune complexes into monocytes/macrophages is hypothesized to be a key event in the pathogenesis of complicated dengue fever. FcγRIA (CD64) and FcγRIIA (CD32), which predominate on the surface of such dengue virus-permissive cells, were...

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Detalhes bibliográficos
Main Authors: Rodrigo, W. W. Shanaka I., Jin, Xia, Blackley, Shanley D., Rose, Robert C., Schlesinger, Jacob J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617290/
https://ncbi.nlm.nih.gov/pubmed/17005690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00792-06
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