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Isolation and Characterization of an Infectious Replication-Competent Molecular Clone of Ecotropic Porcine Endogenous Retrovirus Class C

Xenotransplantation of pig organs is complicated by the existence of polytropic replication-competent porcine endogenous retroviruses (PERV) capable of infecting human cells. The potential for recombination between ecotropic PERV-C and human-tropic PERV-A and PERV-B adds another level of infectious...

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Autori principali: Preuss, Thomas, Fischer, Nicole, Boller, Klaus, Tönjes, Ralf R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617276/
https://ncbi.nlm.nih.gov/pubmed/17005704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01140-06
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