Brd4 Is Required for E2-Mediated Transcriptional Activation but Not Genome Partitioning of All Papillomaviruses

Bromodomain protein 4 (Brd4) has been identified as the cellular binding target through which the E2 protein of bovine papillomavirus type 1 links the viral genome to mitotic chromosomes. This tethering ensures retention and efficient partitioning of genomes to daughter cells following cell division...

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Detalhes bibliográficos
Main Authors: McPhillips, M. G., Oliveira, J. G., Spindler, J. E., Mitra, R., McBride, A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617221/
https://ncbi.nlm.nih.gov/pubmed/16973557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01105-06
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