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Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor

1. Oleamide (cis-9-octadecenoamide) exhibits some cannabimimetic responses despite its low affinities at the currently known cannabinoid receptors. Here we have investigated whether or not it is a vasorelaxant in rat small mesenteric arteries. 2. Oleamide elicited vasorelaxation (EC(50)=1.2±0.2 μM,...

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Detalhes bibliográficos
Main Authors: Hoi, Pui Man, Hiley, C Robin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1616976/
https://ncbi.nlm.nih.gov/pubmed/16415907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706643
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