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Antiviral prodrugs – the development of successful prodrug strategies for antiviral chemotherapy
Following the discovery of the first effective antiviral compound (idoxuridine) in 1959, nucleoside analogues, especially acyclovir (ACV) for the treatment of herpesvirus infections, have dominated antiviral therapy for several decades. However, ACV and similar acyclic nucleosides suffer from low aq...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1615839/ https://ncbi.nlm.nih.gov/pubmed/16284630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706446 |
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