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Simvastatin Inhibits Leukocyte Accumulation and Vascular Permeability in the Retinas of Rats with Streptozotocin-Induced Diabetes

Leukocytes play important roles in the pathogenesis of diabetic retinopathy. Recently, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors have been reported to exert various effects in addition to their lipid-lowering ability. We investigated the effects of simvastatin, a 3-hydroxy-3-methylg...

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Detalhes bibliográficos
Main Authors: Miyahara, Shinsuke, Kiryu, Junichi, Yamashiro, Kenji, Miyamoto, Kazuaki, Hirose, Fumitaka, Tamura, Hiroshi, Katsuta, Hideto, Nishijima, Kazuaki, Tsujikawa, Akitaka, Honda, Yoshihito
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615657/
https://ncbi.nlm.nih.gov/pubmed/15111316
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