Activation of the GLI Oncogene through Fusion with the β-Actin Gene (ACTB) in a Group of Distinctive Pericytic Neoplasms: Pericytoma with t(7;12)

Activation of the GLI oncogene is an important step in the sonic hedgehog signaling pathway, and leads to, eg, tissue-specific cell proliferation during embryogenesis. GLI activity in adult tissues is restricted, but has been identified in various neoplasms, as a result of mutations in the PTCH (pat...

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Main Authors: Dahlén, Anna, Fletcher, Christopher D. M., Mertens, Fredrik, Fletcher, Jonathan A., Perez-Atayde, Antonio R., Hicks, M. John, Debiec-Rychter, Maria, Sciot, Raf, Wejde, Johan, Wedin, Rikard, Mandahl, Nils, Panagopoulos, Ioannis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2004
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615655/
https://ncbi.nlm.nih.gov/pubmed/15111311
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