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Characteristic Multiorgan Pathology of Cystic Fibrosis in a Long-Living Cystic Fibrosis Transmembrane Regulator Knockout Murine Model

The lack of an appropriate animal model with multiorgan pathology characteristic of the human form of cystic fibrosis has hampered our understanding of the pathobiology of the disease. We evaluated multiple organs of congenic C57BL/6J cystic fibrosis transmembrane regulator (Cftr)(−/−) and Cftr(+/+)...

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Detalles Bibliográficos
Main Authors: Durie, Peter R., Kent, Geraldine, Phillips, M. James, Ackerley, Cameron A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615340/
https://ncbi.nlm.nih.gov/pubmed/15039235
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