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The Role of the Cyclin D1-Dependent Kinases in ErbB2-Mediated Breast Cancer

Intact cyclin D1 functions are essential for transformation by erbB2 in tissue culture and murine models. Because cyclin D1 may alter cell proliferation through a variety of mechanisms, we used transgenic models and human tumor samples to particularly address the role of cyclin D1-cyclin-dependent k...

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Main Authors: Yang, Chuanwei, Ionescu-Tiba, Viviana, Burns, Karen, Gadd, Michelle, Zukerberg, Lawrence, Louis, David N., Sgroi, Dennis, Schmidt, Emmett V.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1614725/
https://ncbi.nlm.nih.gov/pubmed/14982856
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